Mistral-Nemo-Instruct-2407 · 11 GPUs measured first-party · llama.cpp · Updated October 2026

What GPU Do You Need for Mistral-Nemo-Instruct-2407?

Mistral-Nemo-Instruct-2407 on 11 GPUs, measured first-party: NVIDIA B300 leads at 196.9 tok/s, T4 trails at 23 tok/s, and it peaked at 8GB of VRAM.

Benchmarked weights: bartowski/Mistral-Nemo-Instruct-2407-GGUF

Fastest we measured
NVIDIA B300

NVIDIA B300

196.9 tok/s on Mistral-Nemo-Instruct-2407, the ceiling. Measured on our bench. 288GB of VRAM, $40,000 at launch.

Pros
  • 196.9 tok/s on Mistral-Nemo-Instruct-2407
  • 288GB, clears the Mistral-Nemo-Instruct-2407 floor
  • Rentable by the hour rather than bought
Cons
  • 1400W board rating
  • Datacenter or workstation hardware, not a retail purchase
Cheapest card that runs it
NVIDIA RTX PRO 6000 Blackwell Workstation Edition

NVIDIA RTX PRO 6000 Blackwell Workstation Edition

164.3 tok/s on Mistral-Nemo-Instruct-2407, lowest launch price that still fits. Measured on our bench. 96GB of VRAM, $8,565 at launch.

Pros
  • 164.3 tok/s on Mistral-Nemo-Instruct-2407
  • 96GB, clears the Mistral-Nemo-Instruct-2407 floor
  • Rentable by the hour rather than bought
Cons
  • 600W board rating
  • Datacenter or workstation hardware, not a retail purchase
196.9tok/s
Fastest: NVIDIA B300
measured, 3-run average
~8GB
VRAM needed (measured peak)
GPU-independent, applies to every card
11
GPUs measured
same pinned harness
0.69tok/s/W
Most efficient: NVIDIA H200
real power sampling, not TDP

What GPU Do You Need for Mistral-Nemo-Instruct-2407?, tok/s by GPU

NVIDIA B300
196.9 tok/s
NVIDIA B200
183.9 tok/s
NVIDIA H200
181.3 tok/s
NVIDIA H100 80GB HBM3
177.4 tok/s
NVIDIA RTX PRO 6000 Blackwell Workstation Edition
164.3 tok/s
NVIDIA A100 80GB SXM4
111.1 tok/s
NVIDIA A100 40GB SXM4
106.3 tok/s
NVIDIA L40S
89.72 tok/s
NVIDIA A10G
57 tok/s
NVIDIA L4
33.01 tok/s
NVIDIA T4
22.98 tok/s

Efficiency: tok/s per 100W drawn

NVIDIA H200
68.6 tok/s / 100W
NVIDIA H100 80GB HBM3
63.26 tok/s / 100W
NVIDIA RTX PRO 6000 Blackwell Workstation Edition
62.65 tok/s / 100W
NVIDIA A100 40GB SXM4
62.25 tok/s / 100W
NVIDIA L4
52.48 tok/s / 100W
NVIDIA B300
48.49 tok/s / 100W
NVIDIA A100 80GB SXM4
48.31 tok/s / 100W
NVIDIA A10G
45.56 tok/s / 100W
NVIDIA B200
43.12 tok/s / 100W
NVIDIA L40S
41.08 tok/s / 100W
NVIDIA T4
36.02 tok/s / 100W

Power is the average pulled during the run, sampled at 1Hz. The fastest card is often not the one here, and for anything left running this is the number that shows up on the bill.

Value: tok/s per $1,000 of MSRP

NVIDIA A10G
20.36 tok/s / $1k
NVIDIA RTX PRO 6000 Blackwell Workstation Edition
19.18 tok/s / $1k
NVIDIA L4
13.2 tok/s / $1k
NVIDIA L40S
11.96 tok/s / $1k
NVIDIA T4
10 tok/s / $1k
NVIDIA A100 40GB SXM4
8.86 tok/s / $1k
NVIDIA A100 80GB SXM4
6.53 tok/s / $1k
NVIDIA H100 80GB HBM3
5.91 tok/s / $1k
NVIDIA H200
5.85 tok/s / $1k
NVIDIA B300
4.92 tok/s / $1k
NVIDIA B200
4.6 tok/s / $1k

Launch price, not street price, so it ages. A speed leaderboard always crowns the most expensive card; this is the counterweight.

Mistral-Nemo-Instruct-2407. Measured tokens per second by GPU

NVIDIA B300196.9
NVIDIA B200183.9
NVIDIA H200181.3
NVIDIA H100 80GB HBM3177.4
NVIDIA RTX PRO 6000 Blackwell Workstation Edition164.3
NVIDIA A100 80GB SXM4111.1
NVIDIA A100 40GB SXM4106.3
NVIDIA L40S89.72
NVIDIA A10G57
NVIDIA L433.01
NVIDIA T422.98
GPUtok/sPrompt t/stok/WAvg power
NVIDIA B300196.93753.80.48406.1 W
NVIDIA B200183.96668.30.43426.5 W
NVIDIA H200181.35996.20.69264.3 W
NVIDIA H100 80GB HBM3177.46042.30.63280.4 W
NVIDIA RTX PRO 6000 Blackwell Workstation Edition164.39002.40.63262.2 W
NVIDIA A100 80GB SXM4111.13016.70.48229.9 W
NVIDIA A100 40GB SXM4106.33001.50.62170.8 W
NVIDIA L40S89.726597.40.41218.4 W
NVIDIA A10G572082.80.46125.1 W
NVIDIA L433.011927.10.5262.9 W
NVIDIA T422.988040.3663.8 W

What the numbers show. Across 11 GPUs measured on our own bench, B300 is fastest at 197 tok/s. The slowest, T4, manages 23.0, so the spread is 8.6x from top to bottom. H200 is the most efficient, 181 tok/s at 264W. Per dollar of launch price, A10G gives the most (20.4 tok/s per $1,000). The fastest card with 16GB or less is T4 at 23.0 tok/s.

How it compares. H100 80GB HBM3: Mistral-Nemo-Instruct-2407 177.4 tok/s, NemoMix-Unleashed-12B 177.3, gemma-2-9b 174.7 (9B), GLM-4.7-Flash 186.1 (31B), Qwen3-Next-80B-A3B 186.2. 2 of 4 beat Mistral-Nemo-Instruct-2407 here. Qwen3-Next-80B-A3B is a mixture-of-experts, so per token it computes only a slice of its size.

Cost on a rented GPU. 1M generated tokens of Mistral-Nemo-Instruct-2407: $1.23 on a A100 40GB SXM4 ($0.47/hr, 2.6 hours), $9.79 on a B300 ($6.94/hr, 85 min, 7.9x the cost).

Mistral-Nemo-Instruct-2407: cost per 1M generated tokens on rented GPUs

NVIDIA A100 40GB SXM4$0.47/hr
NVIDIA T4$0.14/hr
NVIDIA RTX PRO 6000 Blackwell Workstation Edition$1.08/hr
NVIDIA A100 80GB SXM4$0.95/hr
NVIDIA L40S$0.79/hr
NVIDIA H100 80GB HBM3$2.14/hr
NVIDIA L4$0.44/hr
NVIDIA H200$3.59/hr
NVIDIA B200$5.98/hr
NVIDIA B300$6.94/hr
GPUCheapest rateSpeed (tok/s)Cost per 1M generated tokens
NVIDIA A100 40GB SXM4$0.47/hr106.3$1.23
NVIDIA T4$0.14/hr22.98$1.64
NVIDIA RTX PRO 6000 Blackwell Workstation Edition$1.08/hr164.3$1.82
NVIDIA A100 80GB SXM4$0.95/hr111.1$2.37
NVIDIA L40S$0.79/hr89.72$2.45
NVIDIA H100 80GB HBM3$2.14/hr177.4$3.34
NVIDIA L4$0.44/hr33.01$3.70
NVIDIA H200$3.59/hr181.3$5.50
NVIDIA B200$5.98/hr183.9$9.03
NVIDIA B300$6.94/hr196.9$9.79

Cheapest hourly rate we track on RunPod and Vast.ai, divided by the measured speed. Startup time and storage are extra.

Speed tiers for Mistral-Nemo-Instruct-2407. 30+ tok/s: 10 (B300, B200, H200); 10-30 tok/s: 1 (T4). 30 tok/s is roughly where replies outpace reading.

Reading your prompt. Before Mistral-Nemo-Instruct-2407 writes anything it reads the input: 9002.4 tok/s on the RTX PRO 6000 Blackwell Workstation Edition (0.4s for a 4,000-token prompt), 804.0 on the T4 (5.0s). Long documents and big code files feel this number more than the generation speed.

VRAM for Mistral-Nemo-Instruct-2407. Measured peak 7.5GB, so 8GB is the smallest common card size; smallest card it ran on: T4 (16GB). With long context: Q4_K_M 10GB (tested), Q2_K 7GB, Q3_K_M 9GB, Q5_K_M 12GB, Q6_K 14GB.

Power on Mistral-Nemo-Instruct-2407. Most efficient: H200, 264W, 0.40 kWh per 1M generated tokens. Hungriest: B200, 426W, 0.64 kWh. At $0.15/kWh: $0.061 per 1M generated tokens.

Our verdict

Fastest on Mistral-Nemo-Instruct-2407: NVIDIA B300, 196.9 tok/s. Cheapest to rent per job: NVIDIA A100 40GB SXM4, $1.23 per 1M generated tokens.

FAQ

What GPU do I need to run Mistral-Nemo-Instruct-2407?
About 8GB. Smallest card that ran it: NVIDIA T4 (16GB).
How much does it cost to run Mistral-Nemo-Instruct-2407 in the cloud?
$1.23 per 1M generated tokens on a NVIDIA A100 40GB SXM4 at $0.47/hr, cheapest of 10 rentable cards we measured.
Can I run Mistral-Nemo-Instruct-2407 on a 12GB, 16GB or 24GB card?
It used 7.5GB at the precision we tested. 12GB: yes; 16GB: yes; 24GB: yes.
Is the H100 80GB HBM3 or the A100 80GB SXM4 faster for Mistral-Nemo-Instruct-2407?
The H100 80GB HBM3: 177.4 vs 111.1 tok/s, 60% faster on our bench.

How we test

llama.cpp llama-bench at Q4_K_M, 512-token prompt and 128 generated tokens, three runs after a warmup, full GPU offload, with power and VRAM sampled throughout. Token generation is memory-bandwidth-bound, so the ranking tracks bandwidth closely, which makes it a fair guide to cards we haven't run yet.