NVIDIA B300 vs NVIDIA RTX PRO 4500 Blackwell, AI & Machine Learning Comparison
NVIDIA B300 wins 11 of 11 benchmarks, averaging 471.3% faster.
Both cards were measured first-party on our bench, same suite, same test rig.
What the numbers say
The gap is widest in FLUX.1 dev, where NVIDIA B300 leads by 1371% (20.807 vs 1.414 images/min); the closest fight is Qwen3 4B (50% apart).
Benchmark results head-to-head
| Benchmark | NVIDIA B300 | NVIDIA RTX PRO 4500 Blackwell | Difference |
|---|---|---|---|
| Qwen3 4B tok/s | 333.34 | 221.92 | +50% |
| Llama 3.1 8B tok/s | 287.23 | 146.19 | +96% |
| Qwen2.5-Coder 14B tok/s | 158.49 | 80.09 | +98% |
| Qwen3 32B tok/s | 83.68 | 37.61 | +122% |
| Llama 3.3 70B tok/s | 47.97 | 0 | n/a |
| Stable Diffusion XL images/min | 29.2 | 13.1 | +123% |
| Z-Image Turbo images/min | 39.675 | 6.45 | +515% |
| FLUX.1 dev images/min | 20.807 | 1.414 | +1371% |
| FLUX.1 Kontext dev images/min | 10.329 | 0.879 | +1075% |
| Qwen-Image-Edit images/min | 8.14 | 0 | n/a |
| LTX-Video (distilled) frames/s | 31.87 | 3.58 | +790% |
Whole-job comparison
How long each card takes to finish a complete pipeline, not just one model. NVIDIA B300 is faster on 7 of 7; NVIDIA RTX PRO 4500 Blackwell on 0.
| Workflow | NVIDIA B300 | NVIDIA RTX PRO 4500 Blackwell | Difference |
|---|---|---|---|
| 24-frame storyboard | 1.5 min | 6.2 min | NVIDIA B300 4.13x faster |
| 6-panel comic page | 2 min | 11.6 min | NVIDIA B300 5.74x faster |
| 60-second AI short film | 2.2 min | 10.6 min | NVIDIA B300 4.90x faster |
| Character sheet, 12 poses | 2.2 min | 14.6 min | NVIDIA B300 6.56x faster |
| 40-product photo shoot | 6.1 min | 50.1 min | NVIDIA B300 8.26x faster |
| Full codebase review | 6.3 min | 12.5 min | NVIDIA B300 1.98x faster |
| 100-photo restoration batch | 10.2 min | 1 h 54 min | NVIDIA B300 11.19x faster |
Specifications compared
| NVIDIA B300 | NVIDIA RTX PRO 4500 Blackwell | |
|---|---|---|
| VRAM | 288GB | 32GB |
| Architecture | Blackwell Ultra | Blackwell |
| Memory bandwidth | 8 TB/s | 896 GB/s |
| Boost clock | n/a | 2,407 MHz |
| TDP | 1400 W | 200 W |
| Launch MSRP | $40,000 | $2,600 |
| Release | 2025-11-01 | 2025-08-01 |
FAQ
- Which is better for ai & machine learning: NVIDIA B300 or NVIDIA RTX PRO 4500 Blackwell?
- NVIDIA B300 performs better for ai & machine learning, winning 11 of 11 benchmarks in our suite with an average 471.3% advantage.
- What are the main hardware differences between NVIDIA B300 and NVIDIA RTX PRO 4500 Blackwell?
- NVIDIA B300 has 288GB VRAM and a 1400W TDP, while NVIDIA RTX PRO 4500 Blackwell has 32GB VRAM and a 200W TDP.
- Where is the biggest performance difference between NVIDIA B300 and NVIDIA RTX PRO 4500 Blackwell?
- FLUX.1 dev: NVIDIA B300 leads by roughly 1371% (20.807 vs 1.414 images/min) in our testing.
NVIDIA B300 full review · NVIDIA RTX PRO 4500 Blackwell full review · All AI & Machine Learning rankings