NVIDIA GeForce RTX 4080 vs NVIDIA B300, AI & Machine Learning Comparison

NVIDIA GeForce RTX 4080
NVIDIA GeForce RTX 4080
vs
NVIDIA B300
NVIDIA B300

NVIDIA B300 wins 12 of 12 benchmarks, averaging 474.6% faster.

Both cards were measured first-party on our bench, same suite, same test rig.

What the numbers say

The gap is widest in Z-Image Turbo, where NVIDIA B300 leads by 1456% (2.55 vs 39.675 images/min); the closest fight is Qwen3 4B (65% apart); VRAM decides part of this one: NVIDIA B300 runs 140 of our 12 AI workloads while the other card runs 6, models that don't fit score zero.

Benchmark results head-to-head

BenchmarkNVIDIA GeForce RTX 4080NVIDIA B300Difference
Qwen3 4B tok/s201.76333.34-39%
Llama 3.1 8B tok/s127.09287.23-56%
Qwen2.5-Coder 14B tok/s69.93158.49-56%
Qwen3 32B tok/s083.68n/a
Llama 3.3 70B tok/s047.97n/a
Stable Diffusion XL images/min10.1629.2-65%
Z-Image Turbo images/min2.5539.675-94%
FLUX.1 dev images/min020.807n/a
FLUX.1 Kontext dev images/min010.329n/a
Qwen-Image-Edit images/min08.14n/a
LTX-Video (distilled) frames/s3.2331.87-90%
Wan 2.2 5B (720p) frames/s02.94n/a

Whole-job comparison

How long each card takes to finish a complete pipeline, not just one model. NVIDIA GeForce RTX 4080 is faster on 0 of 1; NVIDIA B300 on 1.

WorkflowNVIDIA GeForce RTX 4080NVIDIA B300DifferenceCost per run
Full codebase review14.3 min6.3 minNVIDIA B300 2.27x faster$0.026 vs $0.730

Renting by the hour, NVIDIA GeForce RTX 4080 finishes 1 of 1 cheaper. The quicker card is not automatically the cheaper way to get the work done.

Cost to rent

CardPer hour
NVIDIA GeForce RTX 4080$0.108
NVIDIA B300$6.940

NVIDIA GeForce RTX 4080 is 64.26x cheaper per hour. Cheapest on-demand rate we see across RunPod and Vast.

Specifications compared

NVIDIA GeForce RTX 4080NVIDIA B300
VRAM16GB288GB
ArchitectureAda Lovelace (AD103)Blackwell Ultra
Memory bandwidth716.8 GB/s8 TB/s
Boost clock2,505 MHzn/a
TDP320 W1400 W
Launch MSRP$1,199$40,000
Release2022-11-162025-11-01

FAQ

Which is better for ai & machine learning: NVIDIA GeForce RTX 4080 or NVIDIA B300?
NVIDIA B300 performs better for ai & machine learning, winning 12 of 12 benchmarks in our suite with an average 474.6% advantage.
What are the main hardware differences between NVIDIA GeForce RTX 4080 and NVIDIA B300?
NVIDIA GeForce RTX 4080 has 16GB VRAM and a 320W TDP, while NVIDIA B300 has 288GB VRAM and a 1400W TDP.
Does VRAM matter more than speed between NVIDIA GeForce RTX 4080 and NVIDIA B300?
For AI, yes, NVIDIA B300 fits 4 more of our 12 workloads than NVIDIA GeForce RTX 4080. A model that exceeds VRAM doesn't run slower, it doesn't run at all, so the card that fits the model wins that workload outright.
Where is the biggest performance difference between NVIDIA GeForce RTX 4080 and NVIDIA B300?
Z-Image Turbo: NVIDIA B300 leads by roughly 1456% (2.55 vs 39.675 images/min) in our testing.

NVIDIA GeForce RTX 4080 full review · NVIDIA B300 full review · All AI & Machine Learning rankings